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Mitochondrial Support Supplements

Published on June 6, 2016

All cells, with the exception of red blood cells, contain mitochondria, organelles that produce adenosine triphosphate (ATP), the cellular “energy currency”, from adenosine diphosphate (ADP). In addition, mitochondria are involved in many other processes within the body such as cell signaling and regulation of cellular metabolism. Mitochondrial energy metabolism is a critical part of cellular health and function, and influences overall health.

Optimal mitochondrial function depends on:

  • Quenching of free radicals produced during normal electron transport chain (ETC) activity
  • Integrity of mitochondrial cell membranes
  • The transport of critical metabolites, such as fatty acids, into the mitochondria

                                                             10800 copy

One approach to optimizing mitochondrial function is the provision of micronutrients and antioxidants that support these mechanisms.* K-PAX MitoNutrients is a unique combination of N-acetyl cysteine, acetyl L-carnitine, alpha-lipoic acid and other key nutrients that support mitochondrial functioning, based on the many years of clinical practice and ongoing research studies led by Dr. Kaiser. View the supplement facts.


  • artificial flavoring
  • dairy products
  • gluten
  • preservatives
  • sugar
  • wheat
  • yeast


K-PAX® MitoNutrient® Activator is designed to be taken in combination with K-PAX® MitoNutrients® in those patient populations that require additional energy support.* A differentiating feature is the addition of caffeine along with B-complex vitamins, tyrosine and taurine.Through diligent trial and error, Dr. Kaiser found that some patients did not experience the expected results when taking the mitochondrial nutrients alone, but responded well with the addition of low-dose caffeine.* The low-dose caffeine in K-PAX® MitoNutrient® Activator is designed to act as a catalyst to the basic mitochondrial support nutrient formula.* Preclinical and mechanistic studies support the inclusion of caffeine, notably because caffeine increases hippocampal mitochondrial respiratory rates and may induce mitochondrial biogenesis.*16,17

Individuals requiring additional support may add 1-2 tablets per day of K-PAX® MitoNutrient® Activator in addition to K-PAX® MitoNutrients.® Individuals may take this combination until the desired effects are seen, at which time the K-PAX® MitoNutrient® Activator may be re-evaluated. 


K-PAX® MitoNutrients® and K-PAX® MitoNutrient® Activator supplements are the original formulas designed by Jon D. Kaiser, MD, who is an immune system and mitochondrial health specialist with 25 years of clinical experience exploring the use of micronutrient therapy in support of immune function and optimal energy metabolism.* In addition to his role as clinical faculty at the University of California, San Francisco Medical School, Dr. Kaiser has been performing research focused on the role of supporting mitochondrial health in specific populations that experience varying levels of fatigue and mental alertness.1

The K-PAX® MitoNutrients® formula was developed to support immune and mitochondrial function, with specific emphasis on oxidative stress.* A thorough review of the existing literature of antioxidant effects on mitochondrial health, combined with two decades of clinical integrative medicine experience, led to the final design of K-PAX® MitoNutrients®. 

Call our office toll free: (877)323-FENG to speak to a knowledgeable specialist and place your order.

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